• X4-instrument

NEW! AWSensors X4 Advanced Multichannel QCMD system

Speed-up your work!

The fastest and most sensitive QCMD instrument on the market today.

Main features:

  • Four channels for higher throughput.
  • Integrated temperature control separate for each channel.
  • High sensitivity & low limits of detection.
  • Fast acquisition rate.
  • Low sample volumes.
  • Classical and High‐Frequency QCMD as well as LOVE‐SAW sensor measurements.
  • Comfortable handling and robust measurements with quick‐lock measurement cells.
  • Instrument control and data acquisition via Ethernet.
  • Integrated potentiostat control for simultaneous QCMD and electrochemistry applications.
  • Optional fluidics module(s) with integrated software control.
  • Basic data analysis package and export functions for third‐party software analysis and sleek, space‐saving and lightweight design.
  • Number of cell units (channels) 
  • Type of sensors
  • Measurement modes
    –
  • Number of overtones 
  • Operation frequency range 
  • Max. Frequency resolution (3)
  • Frequency accuracy (3)
  • Temperature control range (4)
  • Temperature stability 
  • Maximum time resolution (5)
  • Normal mass sensitivity in air (6)
  • Normal dissipation sensitivity in air (6)
  • Normal mass sensitivity in liquid (6)
  • Normal dissipation sensitivity in liquid (6)
  • Dimensions, (H x W x D) 
  • Weight 
  • 4
  • QCM, AWS HFF‐QCM, AWS Love‐SAW
  • Tracking mode (single overtone and multiple overtones) (1) High Resolution mode (single overtone and multiple overtones) (2)
  • Up to 7 (fundamental + 6 overtones)  
  • 4 MHz – 160 MHz 
  • 0.1 Hz 
  • ± 0.5 Hz 
  • 15 °C – 45 °C 
  • ± 0.05 °C 
  • 50 sps 
  • 8 pg/cm2
  • 1.71×10-10
  • 0.6 ng/cm2
  • 3.5×10-8
  • 150 mm x 400 mm x 300 mm 
  • smaller than 10 Kg

APPLICATIONS & ASSAYS

Study of:

  • Material properties
  • Biomolecular interactions
  • Protein and immunological systems
  • Lipid systems and removal of lipids
  • Deposition and dissolution of metallic layers
  • Polymer and bio-polymer systems
  • Living cell systems
  • Electrodeposition and corrosion processes
  • Detection of environmental pollutants (pesticides)
  • Toxicity evaluation and ecotoxicity (biofilm formation)
  • Quantifying the rate of the cleaning process and stain removal
  • Detection and quantification of molecular biomarkers
  • Detection of pathogens

Nucleic acid systems

Evaluate different biomolecular interactions:

  • DNA and RNA hybridization studies: detection of mismatches in hybridization, detection of very low quantities in samples.
  • Nucleic acids (e.g. aptamers) interacting with larger molecular systems (protein complexes).

Protein and Immunological systems

Label-free and real-time evaluation of:

  • protein-protein interactions: protein-protein affinity, protein aggregation, antibody-antigen (immunosensor).
  • protein interactions with membranes and other surfaces: protein adsorption on surfaces, enzymatic activity (degradation of substrate films).
  • protein conformational changes.

Lipid systems

Real-time monitoring of:

  • formation of supported lipid membranes;
  • interactions with binding proteins, DNA, peptides or polymers with lipid membranes;
  • degradation of lipid films.

Polymer systems

Real-time study of:

  • formation and characterization of complex (bio)polymeric films: quantification of film thickness, viscoelasticity, or ion/solute transport properties. For instance, it can be applied to describe the course of electropolymerization of a thin film and monitor layer-by-layer assembly of polymers;
  • characterization of nanoparticles adsoption-desorption onto precursor films: kinetics and layer thickness.

Metal systems

Real-time monitoring of electrochemical studies of deposition and dissolution of metallic layers onto the gold electrode of the sensor.

Polymer systems

Real-time study of:

  • formation and characterization of complex (bio)polymeric films: quantification of film thickness, viscoelasticity, or ion/solute transport properties. For instance, it can be applied to describe the course of electropolymerization of a thin film and monitor layer-by-layer assembly of polymers;
  • characterization of nanoparticles adsoption-desorption onto precursor films: kinetics and layer thickness.

Surfactant systems

Real-time monitoring of adsorption of surfactants on different surfaces:

  • characterization of adsorption kinetics, layer thickness and morphology of the adsorbed film (e.g. in tribology studies);
  • study the removal of lipids (stain removal).

Living cell systems

Real-time monitoring of changes in mass and structural properties:

  • cell attachment and spreading onto functionalized sensor surfaces and morphological changes (e.g. alteration cytoskeleton as target in drug screening), and cell detachment from sensor surface as an indicator of cell death.
  • study of cell interaction with the surface of medical devices and biomaterials (study of biocompatibility).
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