AWSensors obtiene ayudas para su Plan de Internacionalización

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30/06/2021. Advanced Wave Sensors S.L. (AWSensors) ha sido beneficiaria de las Ayudas de Seguimiento y Ejecución de las Tutorías de Internacionalización cofinanciadas por el Institut Valencia de Competitividad Empresarial (IVACE) y el Fondo Europeo de Desarrollo Regional (FEDER) cuyo objetivo es mejorar la competitividad de las PYMES de la Comunitat Valenciana. Gracias a este respaldo, AWSensors continuará ejecutando las acciones recogidas en su Plan de Internacionalización y Marketing Digital de 2021, entre las que destacan las estudiadas durante el programa de tutorías de EXPORNET,  en la cual recibimos asesoramiento especializado en posicionamiento internacional, a través del uso de Internet como herramienta comercial de ámbito internacional.

 

 

30 junio 2021

 

QCMD webinar

QCM-D Webinar

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May 24th 2021: AWSensors is pleased to invite you to participate in a QCM-D Scientific Webinar its Distributor Technex, in the BENELUX area, and AWSensors are orginizing. The scientific talk is entitled “Studying Soft Interfaces with Shear Waves: Principles and Applications of the Quartz Crystal Microbalance (QCM-D)” and  will be given by Prof. Diethelm Johannsmann.

 

QCMD Webinar

QCM-D Webinar details

The webinar will take place on Thursday, June 10th, 2021 from 15:00 to 16:30 hrs and it will be free of charge.

To join us, please register on this link: http://eepurl.com/gDLYUD and we will send you the Webinar details.

Speaker’s Short Biography

Diethelm Johannsmann is Professor of Physical Chemistry and the director of the Physical Chemistry Institute at Clausthal University of Technology, Germany. He has made fundamental contributions to the subject of QCM(D), reflected in more than 150 articles, several book chapters, and books. His model is widely used in the analysis of QCM-D data, and he developed free software for QCM-D data analysis and modelling.  You can find more information about his work on his website, https://www.pc.tu-clausthal.de/en/research/johannsmann-group/prof-dr-diethelm-johannsmann/.

 

QCMD Immunosensor

New QCMD Immunosensor Application Note

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May 20th 2021: AWSensors is pleased to invite you to take a look to its new Immunosensor Application Note entitled “QCMD immunosensor for small molecule analytes“.

Summary of the Note

A QCMD-based immunoassay for label-free analysis of small molecule concentration in industrial samples was developed using an AWS QCMD system with surface-modified 5 MHz fundamental frequency QCMD sensors. Accuracy and precision of the immunoassay is evaluated with respect to the industry-standard HPLC reference.

QCMD Immunosensor

Introduction

Accurate, rapid, and cost-effective quantification of small molecule analytes is a pressing problem in various industrial (food, agriculture, environmental protection) and health-related fields. Existing approaches include enzyme-linked immunosorbent assays (ELISAs) and various types of chromatography (e.g., High Performance Liquid Chromatography, HPLC). These approaches require trained personal and centralized laboratories, and their deployment in the field is difficult or impossible.

Quartz Crystal Microbalance with Dissipation, or QCMD, is emerging as a promising technology for the development of fast, portable, automated, and cost-effective immunosensors. Here, we demonstrate a competitive small molecule immunoassay based on the AWSensors QCMD technology.

Download Full Application Note

You can download the full Application Note in pdf file from this link or download it from our Applications Web Page where you can find this and the rest of our Application Notes.

Other references

Publication on AWSensors technology

Preventing Graphene from Restacking via Bioinspired Chemical Inserts: Toward a Superior 2D Micro-supercapacitor Electrode

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Authors: Adnane Bouzina, Hubert Perrot, Ozlem Sel, Catherine Debiemme-Chouvy.

Journal: ACS Appl. Nano Mater. 2021.

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Publication on AWSensors technology

Multifunctional Surfaces for Improving Soft Tissue Integration

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Authors: Adriana Vilaça, Rui M. A. Domingues, Hanna Tiainen, Bárbara B. Mendes, Alejandro Barrantes, Rui L. Reis, Manuela E. Gomes, Manuel Gomez‐Florit.

Journal: Advanced Healthcare Materials, 2021

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Antibodies

Antibody Detection with Quartz Crystal Microbalance

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May 10th 2021: AWSensors offers acoustic sensors for antibody detection. Acoustic biosensor-based immunosensing with  High-Fundamental Frequency Quartz Crystal Microbalance (HFF-QCM) and Love-SAW sensors offers several advantages over Enzyme Linked Immuno Assay (ELISA) or Surface Plasmon Resonance (SPR).

Acoustic sensors antibody detection advantages over ELISA

  • Sensitivity approximately as a standard ELISA or better.
  • Acoustic sensors offer label-free detection of the antibody-antigen binding.
  • Full automation.
  • Pre-calibrated (the user does not need to run the standards. More samples can be run. Reduced cost per sample).
  • Speed.
  • Quantitative real-time /in-situ monitoring.
  • Turn-key solution (no need to specialized detection equipment, reader, or spectrophotometer).
  • Reduced complexity, relaxed requirements for trained personnel.
  • Small volumes (~ 10 of ul per sample).
  • Parallelization and multiple analyte detection through sensor arrays.
  • Sensor re-usablity, leading to reduced assay cost.

Acoustic sensors antibody detection advantages over SPR

  • Better sensitivity.
  • QCM also sees solvent.
  • Provides conformational information of the surface film.
  • Miniaturization and integration into portable systems.
  • Easier to develop parallel and multiple analyte assays through sensor arrays.
  • Affordability.

Therefore, one can develop biosensors based on acoustic immunosensors with highly attractive features in order to rapidly detect pathogens like viruses and bacteria [1], and low molecular weigh compounds.

Application Example

Our Biosensor Application Note  is an application example where we describe a sensitive detection of a low molecular weight pesticide carbaryl using competitive immunoassay with hapen-conjugates immobilized on high-fundamental frequency QCMD sensors, SAMs and monoclonal antibodies (MAb) [2, 3]. As a result, we achieved a very sensitive detection of the carbaryl analyte.

Biosensor

 

References

[1] Surface Generated Acoustic Wave Biosensors for the Detection of Pathogens: A Review 

[2] High-frequency phase shift measurement greatly enhances the sensitivity of QCM immunosensors

[3] Love Wave Immunosensor for the Detection of Carbaryl Pesticide  

Publication on AWSensors technology

Exploring the effect of humidity on thermoplastic starch films using the quartz crystal microbalance

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Authors: Matthew D. Eaton,  Daniel Domene-López,  Qifeng Wang, Mercedes G. Montalbán,  Ignacio Martin-Gullon, Kenneth R. Shull.

Journal: Carbohydrate Polymers, 2021

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Scrutiny of the LiCoO2 Composite Electrode/Electrolyte Interface by Advanced Electrogravimetry and Implications for Aqueous Li-Ion Batteries

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Authors: Wanli Gao, Natacha Krins, Christel Laberty-Robert, Hubert Perrot, and Ozlem Sel

Journal: The Journal of Physical Chemistry, 2021

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Well-Defined Lignin Model Films from Colloidal Lignin Particles

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Authors: Muhammad Farooq , Zou Tao, Juan José Valle-Delgado, Mika Henrikki Sipponen, Maria Morits, Monika Österberg

Journal: Langmuir, 2020

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Publication on AWSensors technology

A Fast Method for Monitoring the Shifts in Resonance Frequency and Dissipation of the QCM Sensors of a Monolithic Array in Biosensing Applications

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Authors: Román Fernández; María Calero; José Vicente García-Narbón; Ilya Reviakine; Antonio Arnau; Yolanda Jiménez

Journal: IEEE Sensors Journal, 2021

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