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SLB

Lipid Bilayers New Application Note

May 15h 2020: AWSensors is pleased to announce the release of its new Application Note on Supported Lipid Bilayers (SLB) entitled “Supported Lipid Bilayer formation followed at low- and high-fundamental frequencies“.

Summary of the Note

The process of supported lipid bilayer (SLB) formation from adsorbed liposomes is a robust biophysical system that is used in laboratories all over the world. Here, it is used to test AWSensors Quartz Crystal Microbalance with Dissipation measurement (QCMD) equipment and high fundamental frequency QCMD sensors. It is shown that the AWSensors QCMD system correctly and quantitatiely reports the frequency and dissipation changes associated with the SLB formation on high- and low-fundamental frequency SiO2-coated sensors. Some differences between the two types of sensors are highlighted.

SLB

Introduction

Quartz crystal microbalance with dissipation measurement, or QCMD, has become a popular technique for research in such disparate fields as material science, biophysics, electrochemistry, and immunosensing. [1] One of the reasons for the wide range of applicability and popularity of QCMD is its ability to provide information about molecular organization (topology and geometry) at solid/liquid interfaces. Specifically, it was shown how the combination of frequency and dissipation could distinguish between different surface-immobilized lipidic assemblies: adsorbed liposomes and supported lipid bilayers (SLBs; Figure 1).[2] This allowed the process of SLB formation from liposomes on SiO2-coated QCMD sensors to be followed in situ.[2] Subsequent studies further showed how the combination of frequency and dissipation measurements on various overtones could be used to study adsorbed liposome deformation [3,4] and detect mutations through the analysis of DNA conformation and length. [5, 6]

Continue reading downloading the full Application Note (below) …


Download Full Application Note

You can download the full Application Note in pdf file from this link or download it from our Applications Web Page where you can find this and the rest of our Application and Technology Notes.

Bioeconomy in Spain

Bioeconomy in the Spanish Public Budget for 2016

Aug 25th 2015

Spanish Parliament starts to debate today the public budget for the next year. So that, we would like to review what are the plans to invest in research and innovation. According to the budget for the Secretary of Innovation, bioeconomy will be one of the priorities for the Spanish Government in 2016.

Bioeconomy figure; food, biomass, public health, energy security, sustainable production, economic and social development

What is bioeconomy?

The bioeconomy definition according to the EFIB (European Forum for the Bioeconomy) is the following:

Bioeconomy encompasses the production of renewable biological resources and their conversion into food, feed, bio-based products and bioenergy via innovative and efficient technologies.

AWSensors tech has important applications in bioeconomy such as environmental monitoring, secure food and water, bioenergy or biomaterials. EU is promoting and funding projects in these fields in order to make the transition to a more resource efficient society and the Spanish Government is following this policy too.

Spain will boost the Bioeconomy Strategy in the public budget to research and development for 2016

Spanish government plans to invest 1,765 million euros in direct aid for innovation projects and 2,446 million euros for loans to enterprises. The resources allocated to direct aid will increase up to 15 per cent over this year and loans will decrease to 9 per cent. The government will give priority to areas considered most in need of development in science and technology such as Andalucia, Extremadura, Canarias, Castilla-La Mancha, Murcia, Galicia and Asturias. Among the actions to be undertaken in these regions, Bioeconomy will be boosted in the agri-food, biomass, bioenergy and bioproducts fields.

Furthermore, the Centre for the Development of Industrial Technology (CDTI), the main driver of innovation in Spain, will have 30 million euros more for direct aid, 35.7% more than the previous year. The Spanish High Council Scientific Research (CSIC) will have 467 million euros next year and the Institute of Health Carlos III (ISCIII), 165 millions.

In spite of this state budget for 2016, Spain is still the 17th european country in gross domestic expenditure on R&D according to Eurostat.